Academic publications

2022

  • Social and occupational outcomes for young people who attend early intervention mental health services: a longitudinal study

    Medical Journal of Australia, 2022

    Frank Iorfino, Joanne S Carpenter, Shane PM Cross, Jacob Crouse, Tracey A Davenport, Daniel F Hermens, Hannah Yee, Alissa Nichles, Natalia Zmicerevska, Adam Guastella, Elizabeth M Scott, Ian B Hickie

    Topics
    Health services
    Outcome research
    Models of care

  • Premature mortality in early-intervention mental health services: a data linkage study protocol to examine mortality and morbidity outcomes in a cohort of help-seeking young people

    BMJ Open, 2022

    Catherine McHugh, Yun Ju Christine Song, Natalia Zmicerevska, Jacob Crouse, Alissa Nichles, Chloe Wilson, Nicholas Ho, Frank Iorfino, Adam Skinner, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Comorbidity
    Suicide

  • Informing the Future of Integrated Digital and Clinical Mental Health Care: Synthesis of the Outcomes From Project Synergy

    JMIR Mental Health, 2022

    Haley M LaMonica, Frank Iorfino, Grace Yeeun Lee, Sarah Piper, Jo-An Occhipinti, Tracey A Davenport, Shane Cross, Alyssa Milton, Laura Ospina-Pinillos, Lisa Whittle, Shelley C Rowe, Mitchell Dowling, Elizabeth Stewart, Antonia Ottavio, Samuel Hockey, Vanessa Wan Sze Cheng, Jane Burns, Elizabeth M Scott, Ian B Hickie

    Topics
    Digital health
    Implementation science
    Health services

  • Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium

    Molecular Psychiatry, 2022

    Laura S van Velzen, Maria R Dauvermann,…, Frank Iorfino,…, ENIGMA Suicidal Thoughts and Behaviours Consortium, Lianne Schmaal

    Topics
    Suicide
    Neurobiology

  • Examining the prevalence of disordered eating in a cohort of young Australians presenting for mental health care at a headspace centre: results from a cross-sectional clinical survey study

    BMJ Open, 2022

    Amy Leigh Burton, Blake Hamilton, Frank Iorfino, Haley M La Monica, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcomes research
    Health services
    Comorbidity

  • Clinical, demographic, and genetic risk factors of treatment-attributed suicidality in >10,000 Australian adults taking antidepressants

    American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2022

    Adrian I Campos, Enda M Byrne, Frank Iorfino, Chiara Fabbri, Ian B Hickie, Cathryn M Lewis, Naomi R Wray, Sarah E Medland, Miguel E Rentería, Nicholas G Martin

    Topics
    Suicide

  • Sex differences in fronto-limbic white matter tracts in youth with mood disorders

    Psychiatry and Clinical Neurosciences, 2022

    Daniel F Hermens, Daniel Jamieson, Lauren Fitzpatrick, Dashiell D Sacks, Frank Iorfino, Jacob J Crouse, Adam J Guastella, Elizabeth M Scott, Ian B Hickie, Jim Lagopoulos

    Topics
    Neurobiology

  • Optimizing Strategies for Improving Mental Health in Victoria, Australia during the COVID-19 Era: A System Dynamics Modelling Study

    International Journal of Environmental Research and Public Health, 2022

    Catherine Vacher, Nicholas Ho, Adam Skinner, Jo Robinson, Louise Freebairn, Grace Yeeun Lee, Frank Iorfino, Ante Prodan, Yun Ju C Song, Jo-An Occhipinti, Ian B Hickie

    Topics
    Complex systems science
    Public health

2021

  • Right Care, First Time: Developing a Theory-Based Automated Protocol to Help Clinically Stage Young People Based on Severity and Persistence of Mental Illness

    Frontiers in Public Health, 2021

    Frank Iorfino, Vanessa Wan Sze Cheng, Shane P Cross, Hannah F Yee, Tracey A Davenport, Elizabeth M Scott, Ian B Hickie

    Topics
    Digital health
    Clinical staging
    Health services

  • Using Digital Technologies to Facilitate Care Coordination Between Youth Mental Health Services: A Guide for Implementation

    Frontiers in Health Services, 2021

    Frank Iorfino, Sarah E Piper, Ante Prodan, Haley M LaMonica, Tracey A Davenport, Grace Yeeun Lee, William Capon, Elizabeth M Scott, Jo-An Occhipinti, Ian B Hickie

    Topics
    Digital health
    Health services

  • The impact of technology-enabled care coordination in a complex mental health system: a local system dynamics model

    Journal of Medical Internet Research, 2021

    Frank Iorfino, Jo-An Occhipinti, Adam Skinner, Tracey Davenport, Shelley Rowe, Ante Prodan, Julie Sturgess, Ian B Hickie

    Topics
    Digital health
    Complex systems science
    Health services

  • Familial aggregation of anxiety disorder subtypes and anxious temperament in the NIMH Family Study of Affective Spectrum Disorders

    Journal of Affective Disorders, 2021

    Frank Iorfino, Ciro Marangoni, Lihong Cui, Daniel F Hermens, Ian B Hickie, Kathleen Ries Merikangas

    Topics
    Clinical phenotyping
    Genetic and family studies
    Comorbidity

  • Implementing a digital health model of care in Australian youth mental health services: protocol for impact evaluation

    BMC Health Services Research, 2021

    Sarah Piper, Tracey A Davenport, Haley LaMonica, Antonia Ottavio, Frank Iorfino, Vanessa Wan Sze Cheng, Shane Cross, Grace Yeeun Lee, Elizabeth Scott, Ian B Hickie

    Topics
    Digital health
    Implementation science
    Health services

  • Reducing youth suicide: systems modelling and simulation to guide targeted investments across the determinants

    BMC Medicine, 2021

    Jo-An Occhipinti, Adam Skinner, Frank Iorfino, Kenny Lawson, Julie Sturgess, Warren Burgess, Tracey Davenport, Danica Hudson, Ian Hickie

    Topics
    Complex systems science
    Suicide
    Public health

  • Optimising the integration of technology-enabled solutions to enhance primary mental health care: a service mapping study

    BMC Health Services Research, 2021

    Haley M LaMonica, Tracey A Davenport, Antonia Ottavio, Shelley C Rowe, Shane P Cross, Frank Iorfino, Tanya A Jackson, Michael A Easton, Jennifer Melsness, Ian B Hickie

    Topics
    Digital health
    Implementation science
    Health services

  • Neurobiology Youth Follow-up Study: protocol to establish a longitudinal and prospective research database using multimodal assessments for current and past mental health treatment-seeking young people within an early intervention service

    BMJ Open, 2021

    Alissa Nichles, Natalia Zmicerevska, Yun Ju Christine Song, Chloe Wilson, Catherine McHugh, Blake Hamilton, Jacob Crouse, Cathrin Rohleder, Joanne Sarah Carpenter, Nicholas Ho, Daniel F Hermens, Naomi Wray, Jan Scott, Kathleen R Merikangas, F Markus Leweke, Dagmar Koethe, Frank Iorfino, Sharon L Naismith, Adam J Guastella, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research

  • Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults

    PLoS One, 2021

    Jan Scott, Jacob J Crouse, Nicholas Ho, Frank Iorfino, Nicholas Martin, Richard Parker, John McGrath, Nathan A Gillespie, Sarah Medland, Ian B Hickie

    Topics
    Clinical phenotyping

  • Using Staged Care to Provide "Right Care First Time" to People With Common Affective Disorders

    Psychiatric Services, 2021

    Vilas Sawrikar, Elizabeth Stewart, Haley M LaMonica, Frank Iorfino, Tracey A Davenport, Shane Cross, Elizabeth Scott, Sharon L Naismith, Loren Mowszowski, Adam Guastella, Ian B Hickie

    Topics
    Clinical staging
    Models of care
    Health services

  • Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning

    BJPsych Open

    Jacob J. Crouse, Joanne S. Carpenter, Frank Iorfino, Tian Lin, Nicholas Ho, Enda M. Byrne, Anjali K. Henders, Leanne Wallace, Daniel F. Hermens, Elizabeth M. Scott, Naomi R. Wray, Ian B. Hickie

    Topics
    Genetic studies
    Clinical phenotyping
    Outcome research

  • Neurocognitive functioning predicts suicidal behaviour in young people with affective disorders

    Journal of Affective Disorders, 2021

    Catherine M McHugh, Frank Iorfino, Jacob J Crouse, Ashleigh Tickell, Alissa Nichles, Natalia Zmicerevska, Nicholas Ho, Rico Lee 2, Daniel F Hermens, Elizabeth Scott, Ian B Hickie

    Topics
    Suicide
    Outcome research

  • White Matter Integrity According to the Stage of Mental Disorder in Youth

    Psychiatric Research: Neuroimaging, 2021

    Dashiell D Sacks, Jim Lagopoulos, Sean N Hatton, Frank Iorfino, Joanne S Carpenter, Jacob J Crouse, Sharon L Naismith, Elizabeth M Scott, Ian B Hickie, Daniel F Hermens

    Topics
    Clinical staging
    Illness progression

2020

  • Predicting self-harm within six months after initial presentation to youth mental health services: A machine learning study

    PLoS One, 2020

    Frank Iorfino, Nicholas Ho, Joanne S Carpenter, Shane P Cross, Tracey A Davenport, Daniel F Hermens, Hannah Yee, Alissa Nichles, Natalia Zmicerevska, Adam Guastella, Elizabeth Scott, Ian B Hickie

    Topics
    Data science
    Digital health
    Health services

  • The Science of Complex Systems Is Needed to Ameliorate the Impacts of COVID-19 on Mental Health

    Frontiers in Psychiatry, 2020

    Jo-An Atkinson, Yun Ju Christine Song, Kathleen R Merikangas, Adam Skinner , Ante Prodan, Frank Iorfino, Louise Freebairn, Danya Rose, Nicholas Ho, Jacob Crouse, Vadim Zipunnikov, Ian B Hickie

    Topics
    Complex systems science

  • Predicting the emergence of full-threshold bipolar I, bipolar II and psychotic disorders in young people presenting to early intervention mental health services

    Psychological Medicine, 2020

    Joanne S Carpenter, Jan Scott, Frank Iorfino, Jacob J Crouse, Nicholas Ho, Daniel F Hermens, Shane P M Cross, Sharon L Naismith, Adam J Guastella, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Suicide

  • Suicidal Thoughts and Behaviors and Their Associations With Transitional Life Events in Men and Women: Findings From an International Web-Based Sample

    JMIR Mental Health, 2020

    Alyssa Clare Milton, Tracey A Davenport, Frank Iorfino, Anna Flego, Jane M Burns, Ian B Hickie

    Topics
    Outcome research
    Suicide

  • Youth Mental Health Tracker: protocol to establish a longitudinal cohort and research database for young people attending Australian mental health services

    BMJ Open, 2020

    Cathrin Rohleder, Yun Ju Christine Song, Jacob J Crouse, Tracey A Davenport, Frank Iorfino, Blake Hamilton, Natalia Zmicerevska, Alissa Nichles, Joanne S Carpenter, Ashleigh M Tickell, Chloe Wilson, Shane P Cross, Adam J Guastella, Dagmar Koethe, F Markus Leweke, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Measurement-based care

  • Cohort profile: the Brain and Mind Centre Optymise cohort: tracking multidimensional outcomes in young people presenting for mental healthcare

    BMJ Open, 2020

    Joanne S Carpenter, Frank Iorfino, Shane Cross, Alissa Nichles, Natalia Zmicerevska, Jacob J Crouse, Jake R Palmer, Alexis E Whitton, Django White, Sharon L Naismith, Adam J Guastella, Daniel F Hermens, Jan Scott, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Comorbidity

  • Transdiagnostic neurocognitive subgroups and functional course in young people with emerging mental disorders: a cohort study

    BJPsych Open, 2020

    Jacob J Crouse, Kate M Chitty, Frank Iorfino, Joanne S Carpenter, Django White, Alissa Nichles, Natalia Zmicerevska, Ashleigh M Tickell, Rico S C Lee, Sharon L Naismith, Elizabeth M Scott, Jan Scott, Daniel F Hermens, Ian B Hickie

    Topics
    Outcome research

  • Modelling associations between neurocognition and functional course in young people with emerging mental disorders: a longitudinal cohort study

    Translational Psychiatry, 2020

    Jacob J Crouse, Kate M Chitty, Frank Iorfino, Joanne S Carpenter, Django White, Alissa Nichles, Natalia Zmicerevska, Adam J Guastella, Elizabeth M Scott, Rico S C Lee, Sharon L Naismith, Jan Scott, Daniel F Hermens, Ian B Hickie

    Topics
    Outcome research

2019

  • Clinical Stage Transitions in Persons Aged 12 to 25 Years Presenting to Early Intervention Mental Health Services With Anxiety, Mood, and Psychotic Disorders

    JAMA Psychiatry, 2019

    Frank Iorfino, Elizabeth M Scott, Joanne S Carpenter, Shane P Cross, Daniel F Hermens, Madhura Killedar, Alissa Nichles, Natalia Zmicerevska, Django White, Adam J Guastella, Jan Scott, Patrick D McGorry, Ian B Hickie

    Topics
    Clinical staging
    Illness progression
    Health services

  • Right care, first time: a highly personalised and measurement‐based care model to manage youth mental health

    Medical Journal of Australia, 2019

    Ian B Hickie, Elizabeth M Scott, Shane P Cross, Frank Iorfino, Tracey A Davenport, Adam J Guastella, Sharon L Naismith, Joanne S Carpenter, Cathrin Rohleder, Jacob J Crouse, Daniel F Hermens, Dagmar Koethe, F Markus Leweke, Ashleigh M Tickell, Vilas Sawrikar, Jan Scott

    Topics
    Health services
    Clinical staging
    Models of care

  • Multidimensional outcomes in youth mental health care: what matters and why?

    Medical Journal of Australia, 2019

    Frank Iorfino, Joanne S Carpenter, Shane P Cross, Tracey A Davenport, Daniel F Hermens, Adam J Guastella, Cathrin Rohleder, Jacob J Crouse, F Markus Leweke, Dagmar Koethe, Sharon L Naismith, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Health services
    Measurement-based care

  • A digital platform designed for youth mental health services to deliver personalized and measurement-based care

    Frontiers in Psychiatry, 2019

    Frank Iorfino, Shane P Cross, Tracey Davenport, Joanne S Carpenter, Elizabeth Scott, Sagit Shiran, Ian B Hickie

    Topics
    Digitial health
    Health services
    Measurement-based care

  • Project Synergy: co-designing technology-enabled solutions for Australian mental health services reform

    Medical Journal of Australia, 2019

    Ian B Hickie, Tracey A Davenport, Jane M Burns, Alyssa C Milton, Laura Ospina-Pinillos, Lisa Whittle, Cristina S Ricci, Larisa T McLoughlin, John Mendoza, Shane P Cross, Sarah E Piper, Frank Iorfino, Haley M LaMonica

    Topics
    Digital health
    Health services
    Implementation science

  • Validation of the InnoWell Platform: Protocol for a Clinical Trial

    JMIR Research Protocols, 2019

    Tracey A Davenport, Haley M LaMonica, Lisa Whittle, Amelia English, Frank Iorfino, Shane Cross, Ian B Hickie

    Topics
    Digital health
    Implementation science
    Models of care

  • What is the prevalence, and what are the clinical correlates, of insulin resistance in young people presenting for mental health care? A cross-sectional study

    BMJ Open, 2019

    Elizabeth M Scott, Joanne S Carpenter, Frank Iorfino, Shane P M Cross, Daniel F Hermens, Jeanne Gehue, Chloe Wilson, Django White, Sharon L Naismith, Adam J Guastella, Ian B Hickie

    Topics
    Health services
    Comorbidity

  • Developing neurocognitive standard clinical care: A study of young adult inpatients

    Psychiatry Research, 2019

    Ashleigh M Tickell, Elizabeth M Scott, Tracey Davenport, Frank Iorfino, Laura Ospina-Pinillos, Django White, Kate Harel, Lisa Parker, Ian B Hickie, Daniel F Hermens

    Topics
    Models of care
    Health services

  • Exploring associations between early substance use and longitudinal socio-occupational functioning in young people engaged in a mental health service

    PLoS One, 2019

    Jacob J Crouse, Kate M Chitty, Frank Iorfino, Django White, Alissa Nichles, Natalia Zmicerevska, Adam J Guastella, Ahmed A Moustafa, Daniel F Hermens, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research

  • Neurocognitive clusters: A pilot study of young people with affective disorders in an inpatient facility

    Journal of Affective Disorders, 2019

    Ashleigh M Tickell, Elizabeth M Scott, Tracey Davenport, Frank Iorfino, Laura Ospina-Pinillos, Kate Harel, Lisa Parker, Ian B Hickie, Daniel F Hermens

    Topics
    Clinical phenotyping
    Models of care

2018

  • Delineating the trajectories of social and occupational functioning of young people attending early intervention mental health services in Australia: a longitudinal study

    British Medical Journal Open, 2018

    Frank Iorfino, Daniel F Hermens, PM Shane, Natalia Zmicerevska, Alissa Nichles, Caro-Anne Badcock, Josine Groot, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Health services
    Functional impairment

  • Prior suicide attempts predict worse clinical and functional outcomes in young people attending a mental health service

    Journal of Affective disorders, 2018

    Frank Iorfino, Daniel F Hermens, Shane PM Cross, Natalia Zmicerevska, Alissa Nichles, Josine Groot, Adam J Guastella, Elizabeth M Scott, Ian B Hickie

    Topics
    Outcome research
    Health services
    Suicidal thoughts and behaviours

  • Personalised Mental Health Care for Young People: Using Past Outcomes to Build Future Solutions

    Doctor of Philosophy Thesis, 2018

    Frank Iorfino

    Topics
    Digital health
    Outcome research
    Health services

2017

  • Using new and emerging technologies to identify and respond to suicidality among help-seeking young people: a cross-sectional study

    Journal of Medical Internet Research, 2017

    Frank Iorfino, Tracey A Davenport, Laura Ospina-Pinillos, Daniel F Hermens, Shane Cross, Jane Burns, Ian B Hickie

    Topics
    Digital health
    Decision-support tool
    Health services

2016

  • The underlying neurobiology of key functional domains in young people with mood and anxiety disorders: a systematic review

    BMC psychiatry, 2016

    Frank Iorfino, Ian B Hickie, Rico SC Lee, Jim Lagopoulos, Daniel F Hermens

    Topics
    Models of care
    Outcome research
    Clinical phenotyping